NONONONONO
What you need is the mother of all ambushes, with a Proximity Grenade minefield and people crouched in windows/around corners so that any of those Crysallid bastards who isn't blown up is then fried to death by Laser Rifles. Have a couple of people on rooves with Heavy Plamsas if possible, but not too many.
I say reload it if you know where the aliens came from.
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