Well, there's a DOSBox tutorial... but here's the shorter version.
You have the game in a "LnD2" folder right (if not rename it)?
Put the LnD2 folder directly to your X: drive (X can be either C:, D:, E: - depends on your hard-disk).
Now install DOSBox.
Run DOSBox!
Type:
mount c X:\LnD2 <press enter> (X is the drive you put the folder on)
c: <press enter>
LD2 <press enter>
And there you go!
If you want full screen press alt+enter (also to go back to window mode again).
BTW - you really should get to know DOSBox - it's THE tool to play good old games like this one
k: