Well as much as I picked up from the net so far, dual-slot graphic cards offer slightly better performance with applications / games, if it is supported, and some are already supporting it. But as Fifth already mentioned, many games (and maybe applications) don not support 2x so there might and will be compatibility problems.
It is an easier solution to get a stronger single graphics card, but in the end it depends on what you mainly intend to use on your computer.
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