[jules-boo]

Ok. This is what I did, but umm, there may be simpler methods out there!
Needless to say atleast it runs from my Vista 64 bit desktop Icon beautifully.
First read th nfo file from th gentleman who is I presume th original uploader.So-o, go into the folder : X.
After reading th nfo txt click on install, naturally this must be run from dosbox having mounted both your Hard drive AND most importantly your Fake CD drive. Ok? So, th command is as follow; (from dosbox)

mount C C:\
and then type:
subst D C:\bioforge\X\Bio
(then)
C:
(then)
Bioforge
Dosbox will complain about using the wildcard C, just ignore it and push on..
Now, once it has been installed somewhere on your C drive i.e C:\Bioforge,
you will have two seperate installations...U need both of then coz Bioforge initializes from the CD-rom first.
So-o lets say you installed the original zip into C:\temp, and lets say U have sucessfully installed onto C, then execute dos-box and type the following and it will launch :
mount C C:\
subst D C:\Temp\Bioforge\X\Bio
(and finally)
Bioforge.exe

Hope this helps,
Jules