I’ve recently managed to get the full Dark Seed II (incl. cut screen) game running in DosBox with Windows 3.11.
I use the S3 864 1.41B5 640x480 256 colors graphics driver, but there’s a conflict between that S3 driver and the Indeo 3.2 video software that Dark Seed II installs (included in Video for Windows 1.1e). It is causing the game/DosBox to crash when playing some of the cut screens – not necessarily every cut screen.
The solution is fairly simple: Get a not so buggy version of Video for Windows 1.1e and install it, so that it replaces the one from Dark Seed II.
Here’s a great guide on
how to install Windows 3.11 on DosBox by Dominus:
http://vogons.zetafleet.com/viewtopic.php?t=9405
There's a link to a working version of Video for Windows 1.1e i that guide.
By the way: No matter what I did, Dark Seed II wouldn’t run in Windows XP Pro SP3. But it runs OK in DosBox with Windows 3.11