It is most certain that you have a cursed item equipped. You can identify items with ORT WIS YLEM (5th circle spell), so I wouldn't use gold or items to pay someone to identify it for you. Aside of that, you should never equip items that are magical before you didn't identify them. Save and identify, if the items isn't magical, load the game to not waste mana.
To open chests or doors I never used the Picklock, instead I either bashed them (with bare fists, they don't get damaged by doors like weapons) or cast EX YLEM if a door is massive and can't be bashed open. Try punching some door you can't open. It can take some time though.
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