Have you tried using some programs like spybot, Lavasoft's Ad-Aware, or even ms antispy?
Since you have look2me you can try using this look2me remover program as well you can get it here
http://www.atribune.org/downloads/l2mfix.exe
if those don't work, you could always head to some of the forums like caslecops or spywareinfo and post a hijackthis log, to see if it can be removed via that route.