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QUOTE(Scatty @ Nov 2 2007, 03:05 AM) [snapback]317952[/snapback]

You can't, neither supposed to run the game from the dos4gw file, because it's used to enable protected mode memory for the game and is used automatically. You need to start the game with another .exe file in that folder.
As about the sound, try Soundblaster, Soundblaster Pro or Soundblaster 16 whichever is available in the configuration program, each other better than previous. Try the following values - Port 220, IRQ 7, DMA 1. If still no sound, try IRQ 5 instead.
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Ok, I tried all three with those settings and still nothing... Any other ideas?